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Identification of 4-[1-[3-chloro-4-[N’-(5-fluoro-2-methylphenyl)ureido]phenylacetyl]-(4S)-fluoro-(2S)-pyrrolidinylmethoxy]benzoic acid as a potent, orally active VLA-4 antagonist

Molecular PharmacologyMedicinal ChemistryPharmaceutical ScienceBioorganic ChemistryBiochemistryMedicineNatural SciencesMechanism Of ActionPharmacological AgentOrganic ChemistryPharmacotherapyActive Vla-4 AntagonistDrug DevelopmentPharmacologyPharmaceutical ChemistryDrug Discovery