Production of the Artemisinin Precursor Amorpha-4,11-diene by Engineered Saccharomyces cerevisiae

Engineering a mevalonate pathway in Escherichia coli for production of terpenoids

Vincent J. J. Martin, Douglas J. Pitera, Sydnor T. Withers et al. · Nature Biotechnology · 2003 · 1.7K citations

Biomanufacturing, Biosynthesis, Engineering +13

Cloning, Yeast Expression, and Characterization of the Coupling of Two Distantly Related Arabidopsis thalianaNADPH-Cytochrome P450 Reductases with P450 CYP73A5

Philippe Urban, Claudia Mignotte, Michaël Kazmaier et al. · Journal of Biological Chemistry · 1997 · 356 citations · Full text

Genetics, Molecular Biology, Plant Biochemistry +19

Molecular Cloning, Expression, and Characterization of Amorpha-4,11-diene Synthase, a Key Enzyme of Artemisinin Biosynthesis in Artemisia annua L.

P. Mercke, Marie Bengtsson, Harro J. Bouwmeester et al. · Archives of Biochemistry and Biophysics · 2000 · 282 citations · Full text

Biosynthesis, Engineering, Biotransformation +9

Effects of overproduction of the catalytic domain of 3-hydroxy-3-methylglutaryl coenzyme A reductase on squalene synthesis in Saccharomyces cerevisiae

Allen Donald, Randolph Y. Hampton, Irving B. Fritz · Applied and Environmental Microbiology · 1997 · 246 citations · Full text

Catalytic Domain, Engineering, Molecular Biology +19

Identification of Intermediates and Enzymes Involved in the Early Steps of Artemisinin Biosynthesis in<i>Artemisia annua</i>

Cinzia M. Bertea, J. Robert Freije, Hester van der Woude et al. · Planta Medica · 2005 · 199 citations · Full text

Engineering, Molecular Biology, Enzymes Involved +19