Concepedia

An enantioselective synthesis of sulphonamide hydroxamic acids as matrix metalloproteinase inhibitors

Robert J. Watson, D. Batty, A. D. BAXTER, Duncan R. Hannah, David Owen, John G. Montana

Tetrahedron Letters · 2002 · 55 citations · 3 references

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Distinct expression profiles of stromelysin-2 (MMP-10), collagenase-3 (MMP-13), macrophage metalloelastase (MMP-12), and tissue inhibitor of metalloproteinases-3 (TIMP-3) in intestinal ulcerations.

Maarit Vaalamo, Marja‐Liisa Karjalainen‐Lindsberg, Pauli Puolakkainen et al. · PubMed · 1998 · 218 citations

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Concise asymmetric routes to 2,2,4-trisubstituted tetrahydrofurans via chiral titanium imide enolates: Key intermediates towards synthesis of highly active azole antifungals SCH 51048 and SCH 56592

Anil K. Saksena, Viyyoor Girijavallabhan, Haiyan Wang et al. · Tetrahedron Letters · 1996 · 53 citations

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Studies directed toward the design of orally active renin inhibitors. 2. Development of the efficacious, bioavailable renin inhibitor (2S)-2-benzyl-3-[[(1-methylpiperazin-4-yl)sulfonyl]propionyl]-3-thiazol-4-yl-L-alanine amide of (2S,3R,4S)-2-amino-1-cyclohexyl-3,4-dihydroxy-6-methylheptane (A-72517)

Saul H. Rosenberg, Kenneth P. Spina, Stephen L. Condon et al. · Journal of Medicinal Chemistry · 1993 · 44 citations · Full text

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