Stephen L. Condon

1,2,3-Trisubstituted cyclopropanes as conformationally restricted peptide isosteres: application to the design and synthesis of novel renin inhibitors

Stephen F. Martin, Richard E. Austin, Christopher J. Oalmann et al. · Journal of Medicinal Chemistry · 1992 · 91 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Dipeptide isosteres. 1. Synthesis of dihydroxyethylene dipeptide isosteres via diastereoselective additions of alkyllithium reagents to N,N-dimethylhydrazones. Preparation of renin and HIV-1 protease inhibitor transition-state mimics

William R. Baker, Stephen L. Condon · The Journal of Organic Chemistry · 1993 · 48 citations

Natural Sciences, Biochemistry, Chemistry +6

Studies directed toward the design of orally active renin inhibitors. 2. Development of the efficacious, bioavailable renin inhibitor (2S)-2-benzyl-3-[[(1-methylpiperazin-4-yl)sulfonyl]propionyl]-3-thiazol-4-yl-L-alanine amide of (2S,3R,4S)-2-amino-1-cyclohexyl-3,4-dihydroxy-6-methylheptane (A-72517)

Saul H. Rosenberg, Kenneth P. Spina, Stephen L. Condon et al. · Journal of Medicinal Chemistry · 1993 · 44 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +6

Structure−Activity Studies for a Novel Series of Tricyclic Substituted Hexahydrobenz[<i>e</i>]isoindole α_1A Adrenoceptor Antagonists as Potential Agents for the Symptomatic Treatment of Benign Prostatic Hyperplasia (BPH)

Michael D. Meyer, Robert J. Altenbach, Fatima Z. Basha et al. · Journal of Medicinal Chemistry · 2000 · 43 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Synthesis of rigid, heterocyclic dipeptide analogs

Dale J. Kempf, Stephen L. Condon · The Journal of Organic Chemistry · 1990 · 26 citations

Natural Sciences, Chemistry, Medicinal Chemistry +8