Anil K. Saksena

Discovery of (1 <i>R</i> ,5 <i>S</i> )- <i>N</i> -[3-Amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]- 3-[2( <i>S</i> )-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2( <i>S</i> )-carboxamide (SCH 503034), a Selective, Potent, Orally Bioavailable Hepatitis C Virus NS3 Protease Inhibitor:  A Potential Therapeutic Agent for the Treatment of Hepatitis C Infection

Srikanth Venkatraman, Stéphane Bogen, Ashok Arasappan et al. · Journal of Medicinal Chemistry · 2006 · 278 citations · Full text

Recent studies on veratrum alkaloids: a new reaction of sodium triacetoxyborohydride [NaBH(OAc)3]

Anil K. Saksena, Pietro Mangiaracina · Tetrahedron Letters · 1983 · 188 citations

New Reaction, Bioorganic Chemistry, Pharmaceutical Chemistry +7

Curcuma longa extract reduces inflammatory and oxidative stress biomarkers in osteoarthritis of knee: a four-month, double-blind, randomized, placebo-controlled trial

Shobhit Srivastava, Anil K. Saksena, Sanjay Khattri et al. · Inflammopharmacology · 2016 · 140 citations

Inflammation, Anti-inflammatory, Pharmacology +9

Characterization of resistance mutations against HCV ketoamide protease inhibitors

Xinchun Tong, Stéphane Bogen, Robert A. Chase et al. · Antiviral Research · 2008 · 127 citations

Drug Discovery, Resistance Mutation (Virology), Resistance Mutations +2

Discovery of the HCV NS3/4A Protease Inhibitor (1<i>R</i>,5<i>S</i>)-<i>N</i>-[3-Amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3- [2(<i>S</i>)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(<i>S</i>)-carboxamide (Sch 503034) II. Key Steps in Structure-Based Optimization

Andrew Prongay, Zhuyan Guo, Nanhua Yao et al. · Journal of Medicinal Chemistry · 2007 · 106 citations · Full text

Protein Assembly, Molecular Biology, Structure-based Optimization +22