An expeditious synthesis of benzimidazole derivatives catalyzed by Lewis acids

The Use of Polyphosphoric Acid in the Synthesis of 2-Aryl- and 2-Alkyl-substituted Benzimidazoles, Benzoxazoles and Benzothiazoles¹

David W. Hein, R. J. Alheim, J. J. Leavitt · Journal of the American Chemical Society · 1957 · 479 citations

Natural Sciences, Chemistry, Medicinal Chemistry +10

Synthesis and Biological Activity of Novel Nonnucleoside Inhibitors of HIV-1 Reverse Transcriptase. 2-Aryl-Substituted Benzimidazoles

Thomas Roth, Marshall Morningstar, Paul L. Boyer et al. · Journal of Medicinal Chemistry · 1997 · 370 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

CCCXVII.—The formation of 2-substituted benziminazoles

Montague Alexandra Phillips · Journal of the Chemical Society (Resumed) · 1928 · 325 citations

Natural Sciences, Chemistry, Organic Chemistry +2

Potential antitumor agents. 59. Structure-activity relationships for 2-phenylbenzimidazole-4-carboxamides, a new class of minimal DNA-intercalating agents which may not act via topoisomerase II

William A. Denny, Gordon W. Rewcastle, Bruce C. Baguley · Journal of Medicinal Chemistry · 1990 · 309 citations

Medicine, Medicinal Chemistry, Pharmacology +12

Synthesis and Angiotensin II Receptor Antagonistic Activities of Benzimidazole Derivatives Bearing Acidic Heterocycles as Novel Tetrazole Bioisosteres

Yasuhisa Kohara, Keiji Kubo, Eiko Imamiya et al. · Journal of Medicinal Chemistry · 1996 · 272 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16