[(4-Hydroxyl-benzo[4,5]thieno[3,2-c]pyridine-3-carbonyl)-amino]-acetic acid derivatives; HIF prolyl 4-hydroxylase inhibitors as oral erythropoietin secretagogues

Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor

Mircea Ivan, Thomas Haberberger, David C. Gervasi et al. · Proceedings of the National Academy of Sciences · 2002 · 556 citations · Full text

Lipid Peroxidation, Alpha Subunits, Redox Biology +19

Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2)

M.A. McDonough, Vivian Li, Emily Flashman et al. · Proceedings of the National Academy of Sciences · 2006 · 365 citations · Full text

Redox Signaling, Crystal Structure, Transcriptional Regulation +14

Mucosal Protection by Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibition

Andreas Robinson, Simon Keely, Jörn Karhausen et al. · Gastroenterology · 2007 · 354 citations · Full text

Inflammation, Medicine, Lipid Peroxidation +5

HIF–prolyl hydroxylase inhibition results in endogenous erythropoietin induction, erythrocytosis, and modest fetal hemoglobin expression in rhesus macaques

Matthew M. Hsieh, Nathaniel S. Linde, Aisha Wynter et al. · Blood · 2007 · 170 citations · Full text

A fluorescence polarization-based interaction assay for hypoxia-inducible factor prolyl hydroxylases

Hyun-Ju Cho, Hyunsung Park, Eun Gyeong Yang · Biochemical and Biophysical Research Communications · 2005 · 29 citations

Aldehyde Dehydrogenase, Biochemistry, Natural Sciences +10