Mucosal Protection by Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibition

Andreas Robinson, Simon Keely, Jörn Karhausen, +3

Gastroenterology

InflammationMedicineLipid PeroxidationHypoxia (Medicine)Mucosal Protection +3

Ursodeoxycholic acid and lithocholic acid exert anti-inflammatory actions in the colon

Joseph B. J. Ward, Natalia Lajczak, Orlaith Kelly, +9

American Journal of Physiology-Gastrointestinal and Liver Physiology

A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis

Emma Beckett, Richard L Stevens, Andrew Jarnicki, +16

Journal of Allergy and Clinical Immunology

InflammationMast Cell DisorderImmunologyCell DeathImmunologic Mechanism +5

MicroRNA-21 drives severe, steroid-insensitive experimental asthma by amplifying phosphoinositide 3-kinase–mediated suppression of histone deacetylase 2

Richard Kim, Jay C. Horvat, James Pinkerton, +15

Journal of Allergy and Clinical Immunology

AsthmaInflammatory Lung DiseaseLung InflammationMedicineImmunology +9

Resolvin E1-induced intestinal alkaline phosphatase promotes resolution of inflammation through LPS detoxification

Eric L. Campbell, Christopher F. MacManus, Douglas J. Kominsky, +6

Proceedings of the National Academy of Sciences

Chronic Inflammatory DiseasesImmunologyEscherichia ColiLps DetoxificationOxidative Stress +17

Chronic cigarette smoke exposure induces systemic hypoxia that drives intestinal dysfunction

Michael Fricker, Bridie J. Goggins, Sean Mateer, +10

JCI Insight

AsthmaImmunologyGastroenterologyPathologyIntestinal Dysfunction +15

Contribution of epithelial innate immunity to systemic protection afforded by prolyl hydroxylase inhibition in murine colitis

Simon Keely, Eric L. Campbell, Alan W. Baird, +7

Mucosal Immunology

InflammationMucosal ImmunologyImmunologyMurine ColitisPathology +8

In Vitro and ex Vivo Intestinal Tissue Models to Measure Mucoadhesion of Poly (Methacrylate) and N-Trimethylated Chitosan Polymers

Simon Keely, Atvinder K. Rullay, Carolyn A. Wilson, +5

Pharmaceutical Research

Tissue EngineeringMeasure MucoadhesionN-trimethylated Chitosan PolymersEngineeringPolymer Science +4

Selective induction of integrin βi by hypoxia‐inducible factor: implications for wound healing

Simon Keely, Louise Glover, Christopher F. MacManus, +4

The FASEB Journal

Chronic Inflammatory DiseasesIntegrin βIEngineeringCell AdhesionImmunology +19

Population based study: atopy and autoimmune diseases are associated with functional dyspepsia and irritable bowel syndrome, independent of psychological distress

Natasha A. Koloski, Michael Jones, Marjorie M. Walker, +5

Alimentary Pharmacology & Therapeutics