Pivotal Role for Acidic Sphingomyelinase in Cerebral Ischemia-Induced Ceramide and Cytokine Production, and Neuronal Apoptosis

Glutamate neurotoxicity and diseases of the nervous system

Dennis W. Choi · Neuron · 1988 · 8K citations

Neurodegenerative Diseases, Neurophysiology, Neuropharmacology +8

TNF activates NF-κB by phosphatidylcholine-specific phospholipase C-induced “Acidic” sphingomyelin breakdown

Stefan Schütze, Karin Potthoff, Thomas Machleidt et al. · Cell · 1992 · 1.1K citations

Inflammation, Signal Transduction, Apoptosis +8

Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors

Annadora J. Bruce, Warren Boling, Mark S. Kindy et al. · Nature Medicine · 1996 · 936 citations

Inflammation, Microglial Responses, Tnf Receptors +11

Mitochondrial Manganese Superoxide Dismutase Prevents Neural Apoptosis and Reduces Ischemic Brain Injury: Suppression of Peroxynitrite Production, Lipid Peroxidation, and Mitochondrial Dysfunction

Jeffrey N. Keller, Mark S. Kindy, Fredrick W. Holtsberg et al. · Journal of Neuroscience · 1998 · 869 citations · Full text

Tumor Necrosis Factor-α

Frank C. Barone, B. Mak Arvin, Ray F. White et al. · Stroke · 1997 · 861 citations