Concepedia

DNA vaccines in sheep: CTLA-4 mediated targeting and CpG motifs enhance immunogenicity in a DNA prime/protein boost strategy

Nicholas J. Kennedy, Terry W. Spithill, Jan M. Tennent, P.R. Wood, David Piedrafita

Vaccine · 2005 · 53 citations · 45 references

DOI

Concepts

References

45

A Toll-like receptor recognizes bacterial DNA

Hiroaki Hemmi, Osamu Takeuchi, Taro Kawai et al. · Nature · 2000 · 6.4K citations

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CTLA-4 is a second receptor for the B cell activation antigen B7.

Peter S. Linsley, William Brady, M Urnes et al. · The Journal of Experimental Medicine · 1991 · 1.7K citations · Full text

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Enhanced T-cell immunogenicity of plasmid DNA vaccines boosted by recombinant modified vaccinia virus Ankara in humans

Samuel McConkey, William H. H. Reece, Vasee Moorthy et al. · Nature Medicine · 2003 · 558 citations

, , +16

Induction of protective immunity in cattle against infection with Fasciola hepatica by vaccination with cathepsin L proteinases and with hemoglobin

John P. Dalton, Sharon McGonigle, T.P. Rolph et al. · Infection and Immunity · 1996 · 250 citations · Full text

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Enhanced responses to a DNA vaccine encoding a fusion antigen that is directed to sites of immune induction

J. S. Boyle, J. L. Brady, Andrew M. Lew · Nature · 1998 · 245 citations

, , +17