Modulation of the IL-10/IL-12 cytokine circuit by interferon-β inhibits the development of epitope spreading and disease progression in murine autoimmune encephalomyelitis

A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

Hervé Groux, Anne O’Garra, Mike Bigler et al. · Nature · 1997 · 3.6K citations

Life Sciences, Immunology, Pathology +12

IL-10 inhibits cytokine production by activated macrophages

David Fiorentino, Albert Zlotnik, Tim R. Mosmann et al. · The Journal of Immunology · 1991 · 2.9K citations · Full text

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Interferon beta‐1b is effective in relapsing‐remitting multiple sclerosis

Neurology · 1993 · 2.1K citations

Pharmacy, Neurology, Pharmacotherapy +14

Interferon beta‐1b is effective in relapsing‐remitting multiple sclerosis

D. W. Paty, D.K.B. Li · Neurology · 1993 · 2K citations · Full text

Pharmacy, Neurology, Pharmacotherapy +14

Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression.

René de Waal Malefyt, John B.A.G. Haanen, Hergen Spits et al. · The Journal of Experimental Medicine · 1991 · 1.9K citations · Full text

Life Sciences, Cell Biology, Immunology +15