Concepedia

Structure-based design and study of non-amyloidogenic, double N-methylated IAPP amyloid core sequences as inhibitors of IAPP amyloid formation and cytotoxicity

Aphrodite Kapurniotu, Anke Schmauder, Konstantinos Tenidis

Journal of Molecular Biology · 2002 · 175 citations · 45 references

DOI

Concepts

References

45

Diffusible, nonfibrillar ligands derived from Aβ <sub>1–42</sub> are potent central nervous system neurotoxins

Mary P. Lambert, Avlin Barlow, Brett A. Chromy et al. · Proceedings of the National Academy of Sciences · 1998 · 3.5K citations · Full text

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Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state

Daniel Burdick, AJ Walencewicz, CG Glabe et al. · Journal of Neuroscience · 1993 · 1.4K citations · Full text

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Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

Alfredo Lorenzo, Bruce A. Yankner · Proceedings of the National Academy of Sciences · 1994 · 1.3K citations

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Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients.

Garth J. S. Cooper, Anthony C. Willis, Anne Clark et al. · Proceedings of the National Academy of Sciences · 1987 · 1.3K citations · Full text

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Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells.

Per Westermark, Christer Wernstedt, Erik Wilander et al. · Proceedings of the National Academy of Sciences · 1987 · 980 citations · Full text

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