Nature · 2013 · 442 citations · 28 references
Life SciencesMicrobiologyMolecular BiologyHost-pathogen InteractionsInnate ImmunityMicrobial PathogenesisBacterial PathogenesisBacterial Virulence FactorsCrispr-cas SystemsInnate Immune ResponseMicrobial Virulence FactorsPathogen Virulence FactorsBacterial Crispr DefenseBacterial Immune Evasion MechanismsCrispr-based Genome EngineeringCrispr-cas RegulationInnate Immunity Evasion
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A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
Martin Jínek, Krzysztof Chylinski, Ines Fonfara et al. · Science · 2012 · 17.3K citations · Full text
CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes
Rodolphe Barrangou, Christophe Fremaux, Hélène Deveau et al. · Science · 2007 · 6.3K citations
CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III
Elitza Deltcheva, Krzysztof Chylinski, Cynthia M. Sharma et al. · Nature · 2011 · 2.6K citations · Full text
The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA
Josiane E. Garneau, Marie-Ève Dupuis, Manuela Villion et al. · Nature · 2010 · 2.3K citations