Concepedia

Assembly of the FKBP51–PHLPP2–AKT signaling complex in cerebral ischemia/reperfusion injury in rats

Xiue Wei, Fengyu Zhang, Kai Wang, Qingxiu Zhang, Liangqun Rong

Brain Research · 2014 · 22 citations · 25 references

DOI

Concepts

References

25

Primary Prevention of Ischemic Stroke

Larry B. Goldstein, Robert J. Adams, Mark J. Alberts et al. · Stroke · 2006 · 1.4K citations · Full text

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PHLPP: A Phosphatase that Directly Dephosphorylates Akt, Promotes Apoptosis, and Suppresses Tumor Growth

Tianyan Gao, Frank B. Furnari, Alexandra C. Newton · Molecular Cell · 2005 · 911 citations · Full text

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FKBP51 Affects Cancer Cell Response to Chemotherapy by Negatively Regulating Akt

Huadong Pei, Liang Li, Brooke L. Fridley et al. · Cancer Cell · 2009 · 732 citations · Full text

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Pathophysiology, treatment, and animal and cellular models of human ischemic stroke

Trent M. Woodruff, John Thundyil, Sung‐Chun Tang et al. · Molecular Neurodegeneration · 2011 · 597 citations · Full text

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PHLPP and a Second Isoform, PHLPP2, Differentially Attenuate the Amplitude of Akt Signaling by Regulating Distinct Akt Isoforms

John Brognard, Emma Sierecki, Tianyan Gao et al. · Molecular Cell · 2007 · 578 citations · Full text

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