Concepedia

Administration of two macrophage-derived interferon-γ-inducing factors (IL-12 and IL-15) induces a lethal systemic inflammatory response in mice that is dependent on natural killer cells but does not require interferon-γ

Jennifer Biber, Saad Jabbour, Robin Parihar, Julie Dierksheide, Heinz Baumann, Page Bouchard, Michael A. Caligiuri, William E. Carson

Cellular Immunology · 2002 · 20 citations · 44 references

DOI

Concepts

References

44

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

David Kägi, Birgit Ledermann, Kurt Bürki et al. · Nature · 1994 · 1.8K citations

, , +15

Multiple Defects of Immune Cell Function in Mice with Disrupted Interferon-γ Genes

Dyana K. Dalton, Sharon Pitts-Meek, Satish Keshav et al. · Science · 1993 · 1.7K citations

, , +17

Targeted Disruption of the Mouse Stat1 Gene Results in Compromised Innate Immunity to Viral Disease

Joan E. Durbin, Renée Hackenmiller, M. Celeste Simon et al. · Cell · 1996 · 1.6K citations · Full text

, , +17

Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice

Mark H. Kaplan, Ya‐Lin Sun, Timothy Hoey et al. · Nature · 1996 · 1.2K citations

, , +16

Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells

William E. Thierfelder, Jan M. van Deursen, Koh Yamamoto et al. · Nature · 1996 · 1.2K citations

, , +16