Concepedia

Discovery of novel hydroxamates as highly potent tumor necrosis factor-α converting enzyme inhibitors. Part II: Optimization of the S3′ pocket

Robert Mazzola, Zhaoning Zhu, Lisa Sinning, Brian A. McKittrick, Brian J. Lavey, James Spitler, Joseph A. Kozlowski, Shih Neng-Yang, Guowei Zhou, Zhuyan Guo,

Bioorganic & Medicinal Chemistry Letters · 2008 · 32 citations · 19 references

DOIFull text

Open access

Concepts

References

19

A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells

Roy A. Black, Charles T. Rauch, Carl J. Kozlosky et al. · Nature · 1997 · 3.1K citations

, , +14

Infliximab and Methotrexate in the Treatment of Rheumatoid Arthritis

Peter E. Lipsky, Désirée van der Heijde, E. William St. Clair et al. · New England Journal of Medicine · 2000 · 3K citations · Full text

, , +14

A Comparison of Etanercept and Methotrexate in Patients with Early Rheumatoid Arthritis

Joan M. Bathon, Richard W. Martin, Roy Fleischmann et al. · New England Journal of Medicine · 2000 · 1.8K citations · Full text

, , +12

Treatment of Rheumatoid Arthritis with a Recombinant Human Tumor Necrosis Factor Receptor (p75)–Fc Fusion Protein

Larry W. Moreland, Scott W. Baumgartner, Michael Schiff et al. · New England Journal of Medicine · 1997 · 1.6K citations · Full text

, , +17

Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α

Marcia L. Moss, S.-L. Catherine Jin, Marcos E. Milla et al. · Nature · 1997 · 1.6K citations

, , +11