Signal Transducer and Activator of Transcription 4 Is Required for the Transcription Factor T-bet to Promote T Helper 1 Cell-Fate Determination

A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment

Susanne J. Szabo, Sean Kim, Gina L. Costa et al. · Cell · 2000 · 3.5K citations · Full text

Life Sciences, Immunology, Molecular Biology +13

Development of T _H 1 CD4 ⁺ T Cells Through IL-12 Produced by <i>Listeria</i> -Induced Macrophages

Chyi‐Song Hsieh, S E Macatonia, Catherine S. Tripp et al. · Science · 1993 · 3.1K citations

Life Sciences, Immunology, Microbiology +17

Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice

Mark H. Kaplan, Ya‐Lin Sun, Timothy Hoey et al. · Nature · 1996 · 1.2K citations

Life Sciences, Immunology, Pathology +16

Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells

William E. Thierfelder, Jan M. van Deursen, Koh Yamamoto et al. · Nature · 1996 · 1.2K citations

Life Sciences, Cell Biology, Immunology +16

Distinct Effects of T-bet in T _H 1 Lineage Commitment and IFN-γ Production in CD4 and CD8 T Cells

Susanne J. Szabo, Brandon M. Sullivan, Claudia Stemmann et al. · Science · 2002 · 1.2K citations

Life Sciences, Cell Biology, Immunology +17