Effects of racemic, S- and R-indobufen on cyclooxygenase and lipoxygenase activities in human whole Mood

Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides.

Mats Hámberg, Jan Olof Svensson, B Samuelsson · Proceedings of the National Academy of Sciences · 1975 · 3.1K citations · Full text

Medicine, Pharmacology, Biochemical Pharmacology +14

Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves.

André DeLÉAN, Peter J. Munson, David Rodbard · American Journal of Physiology-Endocrinology and Metabolism · 1978 · 2.4K citations

Medicine, Biostatistics, Pharmacology +17

Selective Cumulative Inhibition of Platelet Thromboxane Production by Low-dose Aspirin in Healthy Subjects

Paola Patrignani, Paola Filabozzi, Carlo Patrono · Journal of Clinical Investigation · 1982 · 941 citations · Full text

Medicine, Hematology, Pharmacology +15

L-663,536 (MK-886) (3-[1-(4-chlorobenzyl)-3-<i>t</i>-butyl-thio-5-isopropylindol-2-yl]-2,2-dimethylpropanoic acid), a novel, orally active leukotriene biosynthesis inhibitor

John W. Gillard, A W Ford‐Hutchinson, Chi-Chung Chan et al. · Canadian Journal of Physiology and Pharmacology · 1989 · 328 citations

Medicine, Biochemistry, Pharmacology +14

Translocation of 5-lipoxygenase to the membrane in human leukocytes challenged with ionophore A23187.

Carol A. Rouzer, Stacia Kargman · Journal of Biological Chemistry · 1988 · 321 citations · Full text

Life Sciences, Biochemistry, Cell Biology +13