Combined homozygous factor H and heterozygous C2 deficiency in an Italian family

Human complement C3b inactivator: isolation, characterization, and demonstration of an absolute requirement for the serum protein beta1H for cleavage of C3b and C4b in solution.

Michael K. Pangburn, Robert D. Schreiber, Hans J. Müller‐Eberhard · The Journal of Experimental Medicine · 1977 · 684 citations · Full text

Life Sciences, Biochemistry, Immunology +14

Relation of putative thioester bond in C3 to activation of the alternative pathway and the binding of C3b to biological targets of complement.

Michael K. Pangburn, Hans J. Müller‐Eberhard · The Journal of Experimental Medicine · 1980 · 336 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

HOMOZYGOUS DEFICIENCY OF C3 IN A PATIENT WITH REPEATED INFECTIONS

Chester A. Alper, Harvey R. Colten, Fred S. Rosen et al. · The Lancet · 1972 · 271 citations

Life Sciences, Genetics, Immunology +10

Complement receptor is an inhibitor of the complement cascade.

Kei Iida, Victor Nussenzweig · The Journal of Experimental Medicine · 1981 · 264 citations · Full text

Life Sciences, Biochemistry, Immunology +14

Relationship between C4 null genes, HLA-D region antigens, and genetic susceptibility to systemic lupus erythematosus in Caucasian and Black Americans

Paul F. Howard, Marc C. Hochberg, Wilma Β. Bias et al. · The American Journal of Medicine · 1986 · 228 citations

Life Sciences, Genetics, Immunology +17