An analysis of genetic toxicity, reproductive and developmental toxicity, and carcinogenicity data: I. Identification of carcinogens using surrogate endpoints

Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.

Joyce McCann, E Choi, Edna N. Yamasaki et al. · Proceedings of the National Academy of Sciences · 1975 · 3.3K citations · Full text

Pharmacy, Environmental Sciences, Toxicology +16

Prediction of Chemical Carcinogenicity in Rodents from in Vitro Genetic Toxicity Assays

Raymond W. Tennant, Barry H. Margolin, Michael D. Shelby et al. · Science · 1987 · 817 citations

Pharmacy, Genetics, Toxicology +17

Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens

David Kirkland, Marilyn J. Aardema, L.M. Henderson et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2005 · 752 citations

Pharmacy, Toxicology, Genetic Toxicology +9

Definitive relationships among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the U.S. NTP

John Ashby, Raymond W. Tennant · Mutation Research/Reviews in Genetic Toxicology · 1991 · 685 citations

Pharmacy, Chemistry, Toxicology +15

Describing the validity of carcinogen screening tests

Jeremy Cooper, Rodolfo Saracci, Philip Cole · British Journal of Cancer · 1979 · 350 citations

Medicine, Oncology, Toxicology +12