Concepedia

Surrogate Endpoints

Surrogate Endpoint is a biomarker or intermediate clinical endpoint used in biomedical research to substitute for a direct measure of clinically meaningful patient outcomes, differing from traditional endpoints by its indirect inference of therapeutic effect based on established epidemiological, pathophysiological, or clinical evidence.

1.7K

Publications

104.3K

Citations

10.7K

Authors

2.7K

Institutions

Publications per year

2017–2026

539

Variants

Surrogate Markers

Parents

Publications

1.7K

Susceptibility to Exacerbation in Chronic Obstructive Pulmonary Disease

John R. Hurst, Jørgen Vestbo, Antonio Anzueto et al. · New England Journal of Medicine · 2010 · 3K citations · Full text

, , +14

Surrogate endpoints in clinical trials: Definition and operational criteria

Ross L. Prentice · Statistics in Medicine · 1989 · 2K citations

, , +14

Therapeutic monitoring of vancomycin for serious methicillin-resistant <i>Staphylococcus aureus</i> infections: A revised consensus guideline and review by the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists

Michael J. Rybak, Jennifer Lê, Thomas P. Lodise et al. · American Journal of Health-System Pharmacy · 2020 · 1.1K citations · Full text

, , +17

Determinants of Tumor Response and Survival With Erlotinib in Patients With Non—Small-Cell Lung Cancer

Román Pérez-Soler, Abraham Chachoua, Lisa A. Hammond et al. · Journal of Clinical Oncology · 2004 · 1.1K citations · Full text

, , +16

Association between the number of eggs and live birth in IVF treatment: an analysis of 400 135 treatment cycles

Sesh Kamal Sunkara, V. Rittenberg, Nick Raine‐Fenning et al. · Human Reproduction · 2011 · 930 citations

, , +15

1–5 of 1.7K

Authors

10.7K

  1. MB
    Marc Buyse

    International Drug Development Institute (Belgium), Belgium

    24 publications · 2.8K citations

    20

    h-index

  2. GM
    Geert Molenberghs

    Hasselt University, Belgium

    27 publications · 2.1K citations

    19

    h-index

  3. TB
    Tomasz Burzykowski

    Hasselt University, Belgium

    20 publications · 2.1K citations

    18

    h-index

  4. PB
    Peter B. Gilbert

    Fred Hutch Cancer Center, United States

    16 publications · 947 citations

    16

    h-index

  5. DA
    David A. Lomas

    GlaxoSmithKline (United States), United States

    15 publications · 4.9K citations

    14

    h-index

1–5 of 10.7K

Institutions

2.7K

  1. Harvard University

    Cambridge, United States

    33 h-index

    133 publications

    16.3K citations

  2. Inserm

    Paris, France

    33 h-index

    204 publications

    13.2K citations

  3. University of Washington

    Seattle, United States

    33 h-index

    78 publications

    7.1K citations

  4. Brigham and Women's Hospital

    Boston, United States

    27 h-index

    94 publications

    12.8K citations

  5. Johns Hopkins University

    Baltimore, United States

    26 h-index

    109 publications

    8.6K citations

  6. National Institutes of Health

    Bethesda, United States

    24 h-index

    73 publications

    5.6K citations

  7. University of Michigan

    Ann Arbor, United States

    24 h-index

    115 publications

    14.4K citations

  8. University College London

    London, United Kingdom

    24 h-index

    91 publications

    11.8K citations

1–8 of 2.7K

Venues

  1. PubMed

    Repository · 85 publications · 3.6K citations

    32

    h-index

  2. PLoS ONE

    43 publications · 1.8K citations

    26

    h-index

  3. Statistics in Medicine

    37 publications · 4.9K citations

    25

    h-index

  4. Biometrics

    30 publications · 1.9K citations

    21

    h-index

  5. Journal of Clinical Oncology

    27 publications · 3K citations

    17

    h-index

1–5