Edwin J. Matthews

A New Highly Specific Method for Predicting the Carcinogenic Potential of Pharmaceuticals in Rodents Using EnhancedMCASEQSAR-ES Software

Edwin J. Matthews, Joseph F. Contrera · Regulatory Toxicology and Pharmacology · 1998 · 142 citations

Predictive Toxicology, Preclinical Drug Evaluation, Medicine +10

An analysis of genetic toxicity, reproductive and developmental toxicity, and carcinogenicity data: I. Identification of carcinogens using surrogate endpoints

Edwin J. Matthews, Naomi L. Kruhlak, Michael C. Cimino et al. · Regulatory Toxicology and Pharmacology · 2005 · 132 citations

Genetic Toxicity, Predictive Toxicology, Genetics +14

Transformation of BALB/c-3T3 cells: V. Transformation responses of 168 chemicals compared with mutagenicity in Salmonella and carcinogenicity in rodent bioassays.

Edwin J. Matthews, Judson W. Spalding, Raymond W. Tennant · Environmental Health Perspectives · 1993 · 97 citations · Full text

Rodent Bioassays, Immunology, Toxicological Mechanism +21

An analysis of genetic toxicity, reproductive and developmental toxicity, and carcinogenicity data: II. Identification of genotoxicants, reprotoxicants, and carcinogens using in silico methods

Edwin J. Matthews, Naomi L. Kruhlak, Michael C. Cimino et al. · Regulatory Toxicology and Pharmacology · 2005 · 96 citations

Predictive Toxicology, Medicine, Pathology +8

Predicting the carcinogenic potential of pharmaceuticals in rodents using molecular structural similarity and E-state indices

Joseph F. Contrera, Edwin J. Matthews, R. Benz · Regulatory Toxicology and Pharmacology · 2003 · 93 citations

Tumor Biology, Predictive Toxicology, E-state Indices +10