Concepedia

Using siRNA Technique to Generate Transgenic Animals with Spatiotemporal and Conditional Gene Knockdown

Hung‐Shu Chang, Ching-Hui Lin, Yu‐Chi Chen

American Journal Of Pathology · 2004 · 67 citations · 12 references

DOI

Concepts

References

12

A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference

Douglas A. Rubinson, Christopher P. Dillon, Adam V. Kwiatkowski et al. · Nature Genetics · 2003 · 1.5K citations

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Stable suppression of tumorigenicity by virus-mediated RNA interference

Thijn R. Brummelkamp, René Bernards, Reuven Agami · Cancer Cell · 2002 · 1.1K citations · Full text

, , +14

Stable suppression of gene expression by RNAi in mammalian cells

Patrick J. Paddison, Amy A. Caudy, Gregory J. Hannon · Proceedings of the National Academy of Sciences · 2002 · 550 citations · Full text

, , +9

A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA

Gustavo Tiscórnia, Oded Singer, Masahito Ikawa et al. · Proceedings of the National Academy of Sciences · 2003 · 540 citations · Full text

, , +17

Interactions between double-stranded RNA regulators and the protein kinase DAI.

Lisa Manche, Simon R. Green, Christian Schmedt et al. · Molecular and Cellular Biology · 1992 · 477 citations · Full text

, , +11