Gap costs for multiple sequence alignment

A general method applicable to the search for similarities in the amino acid sequence of two proteins

Saul B. Needleman, Christian D. Wunsch · Journal of Molecular Biology · 1970 · 11.5K citations

Life Sciences, Biochemistry, Bioinformatics +13

An improved algorithm for matching biological sequences

Osamu Gotoh · Journal of Molecular Biology · 1982 · 1.8K citations

Life Sciences, Bioinformatics, Biology +14

Optimal alignments in linear space

Eugene W. Myers, Webb Miller · Computer applications in the biosciences · 1988 · 1.2K citations

Life Sciences, Bioinformatics, Biology +13

Minimal Mutation Trees of Sequences

David Sankoff · SIAM Journal on Applied Mathematics · 1975 · 598 citations

Life Sciences, Bioinformatics, Evolutionary Biology +11

The Multiple Sequence Alignment Problem in Biology

Humberto Carrillo-Calvet, David J. Lipman · SIAM Journal on Applied Mathematics · 1988 · 531 citations

Life Sciences, Biology, Molecular Biology +12