Concepedia

Multiple Sequence Alignment Gap Penalties

Multiple Sequence Alignment Gap Penalties is a computational scoring mechanism used in bioinformatics that assigns specific costs or penalties to the insertion or deletion of gaps in multiple sequence alignments, distinguishing it from pairwise gap penalty methods by accounting for evolutionary, structural, and positional dependencies across three or more biological sequences simultaneously.

22

Publications

2.4K

Citations

42

Authors

33

Institutions

Publications per year

2017–2026

0

Parents

Publications

22

An algorithm for progressive multiple alignment of sequences with insertions

Ari Löytynoja, Nick Goldman · Proceedings of the National Academy of Sciences · 2005 · 969 citations · Full text

, , +14

DECIPHER: harnessing local sequence context to improve protein multiple sequence alignment

Erik S. Wright · BMC Bioinformatics · 2015 · 422 citations · Full text

, , +14

The size distribution of insertions and deletions in human and rodent pseudogenes suggests the logarithmic gap penalty for sequence alignment

Xun Gu, Wen‐Hsiung Li · Journal of Molecular Evolution · 1995 · 160 citations

, , +17

Gap costs for multiple sequence alignment

Stephen F. Altschul · Journal of Theoretical Biology · 1989 · 140 citations

, , +9

Optimal sequence alignment allowing for long gaps

Osamu Gotoh · Bulletin of Mathematical Biology · 1990 · 90 citations

, , +10

1–5 of 22

Authors

42

  1. OG
    Osamu Gotoh

    Saitama Cancer Center, Japan

    3 publications · 206 citations

    3

    h-index

  2. SF
    Stephen F. Altschul

    National Institutes of Health, United States

    3 publications · 233 citations

    3

    h-index

  3. HY
    Hayato Yamana

    Waseda University, Japan

    1 publications · 35 citations

    1

    h-index

  4. AC
    Alberto Caprara

    University of Bologna, Italy

    1 publications · 34 citations

    1

    h-index

  5. WJ
    Winfried Just

    Ohio University, United States

    1 publications · 10 citations

    1

    h-index

1–5 of 42

Institutions

33

  1. National Institutes of Health

    Bethesda, United States

    3 h-index

    3 publications

    107 citations

  2. Saitama Cancer Center

    Saitama, Japan

    2 h-index

    2 publications

    171 citations

  3. National Center for Biotechnology Information

    Bethesda, United States

    2 h-index

    2 publications

    93 citations

  4. University of Houston

    Houston, United States

    1 h-index

    2 publications

    110 citations

  5. The University of Texas Health Science Center at Houston

    Houston, United States

    1 h-index

    2 publications

    320 citations

  6. Harvard University

    Cambridge, United States

    1 h-index

    1 publications

    80 citations

  7. Fırat University

    Elâzığ, Türkiye

    1 h-index

    1 publications

    55 citations

  8. University of Calgary

    Calgary, Canada

    1 h-index

    2 publications

    110 citations

1–8 of 33

Venues

  1. BMC Bioinformatics

    2 publications · 457 citations

    2

    h-index

  2. Gene

    2 publications · 66 citations

    2

    h-index

  3. Bulletin of Mathematical Biology

    2 publications · 171 citations

    2

    h-index

  4. Bioinformatics

    2 publications · 54 citations

    2

    h-index

  5. 1

    h-index

1–5