Tubulysin analogs incorporating desmethyl and dimethyl tubuphenylalanine derivatives

Tubulysins, New Cytostatic Peptides from Myxobacteria Acting on Microtubuli. Production, Isolation, Physico-chemical and Biological Properties.

Florenz Sasse, HEINRICH SIEINMETZ, J. R. HEIL et al. · The Journal of Antibiotics · 2000 · 250 citations · Full text

Isolation, Crystal and Solution Structure Determination, and Biosynthesis of Tubulysins—Powerful Inhibitors of Tubulin Polymerization from Myxobacteria

Heinrich Steinmetz, Nicole Glaser, Eberhardt Herdtweck et al. · Angewandte Chemie International Edition · 2004 · 161 citations

Bioorganic Chemistry, Cell Death, Solution Structure Determination +19

Mechanism of Action of Tubulysin, an Antimitotic Peptide from Myxobacteria

Mohamed W. Khalil, Florenz Sasse, Heinrich Lünsdorf et al. · ChemBioChem · 2006 · 157 citations

Immunology, Peptide Science, Cytoskeleton +18

Biological evaluation of tubulysin A: a potential anticancer and antiangiogenic natural product

Gurmeet Kaur, Melinda G. Hollingshead, Susan L. Holbeck et al. · Biochemical Journal · 2006 · 130 citations · Full text

Chemoprevention Strategy, Pathology, Tumor Biology +20

The Total Synthesis of Tubulysin D

Hillary M. Peltier, Jeffrey McMahon, Andrew W. Patterson et al. · Journal of the American Chemical Society · 2006 · 126 citations

Combinatorial Chemistry, Medicinal Chemistry, Biosynthesis +12