Identification and chemical profiling of monacolins in red yeast rice using high-performance liquid chromatography with photodiode array detector and mass spectrometry

Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent.

Alfred W. Alberts, J Chen, G. W. Kuron et al. · Proceedings of the National Academy of Sciences · 1980 · 1.6K citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Competitive inhibition of 3‐hydroxy‐3‐methylglutaryl coenzyme a reductase by ML‐236A and ML‐236B fungal metabolites, having hypocholesterolemic activity

Akira Endo, Masao Kuroda, Kazuhiko Tanzawa · FEBS Letters · 1976 · 802 citations

Life Sciences, Biochemistry, Pharmacology +16

Monacolin K, a new hypocholesterolemic agent produced by a Monascus species.

Akira Endo · The Journal of Antibiotics · 1979 · 670 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +11

Modulation of Polyketide Synthase Activity by Accessory Proteins During Lovastatin Biosynthesis

Jonathan Kennedy, Karine Auclair, Steven G. Kendrew et al. · Science · 1999 · 660 citations

Life Sciences, Biochemistry, Enzymology +16

Cholesterol-lowering effects of a proprietary Chinese red-yeast-rice dietary supplement

David Heber, Ian Yip, Judith Ashley et al. · American Journal of Clinical Nutrition · 1999 · 500 citations · Full text

Agriculture, Nutrition, Nutritional Sciences +14