Concepedia

MKP-1: A negative feedback effector that represses MAPK-mediated pro-inflammatory signaling pathways and cytokine secretion in human airway smooth muscle cells

Melanie Manetsch, Wenchi Che, Yang Chen, Alaina J. Ammit

Cellular Signalling · 2011 · 57 citations · 22 references

DOI

Concepts

References

22

MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo

Hong Sun, Catherine H. Charles, Lester F. Lau et al. · Cell · 1993 · 1.2K citations

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Cytokines in symptomatic asthma airways

David H. Broide, A CUOMO, David Coburn et al. · Journal of Allergy and Clinical Immunology · 1992 · 742 citations

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Antiinflammatory effects of dexamethasone are partly dependent on induction of dual specificity phosphatase 1

Sonya Abraham, Toby Lawrence, Anna Kleiman et al. · The Journal of Experimental Medicine · 2006 · 429 citations · Full text

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Essential Role of MAPK Phosphatase-1 in the Negative Control of Innate Immune Responses

Konstantin V. Salojin, Iris B. Owusu, Karen Millerchip et al. · The Journal of Immunology · 2006 · 336 citations · Full text

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Restraint of Proinflammatory Cytokine Biosynthesis by Mitogen-Activated Protein Kinase Phosphatase-1 in Lipopolysaccharide-Stimulated Macrophages

Peili Chen, Ji Li, Janice Barnes et al. · The Journal of Immunology · 2002 · 285 citations

, , +17