Increased Expression of Alpha-Synuclein by SNCA Duplication is Associated with Resistance to Toxic Stimuli

α-Synuclein Locus Triplication Causes Parkinson's Disease

Andrew Singleton, Matthew J. Farrer, Janel Johnson et al. · Science · 2003 · 4.4K citations

Life Sciences, Genetics, Neuroscience +15

A Drosophila model of Parkinson's disease

Mel Β. Feany, Welcome Bender · Nature · 2000 · 2.1K citations

Life Sciences, Neurobiology, Neuroscience +12

α-synuclein locus duplication as a cause of familial Parkinson's disease

Marie‐Christine Chartier‐Harlin, Jennifer M. Kachergus, Christophe Roumier et al. · The Lancet · 2004 · 2K citations

Life Sciences, Genetics, Neuroscience +14

Causal relation between α-synuclein locus duplication as a cause of familial Parkinson's disease

Pablo Ibáñez, A-M Bonnet, Béatrice Debarges et al. · The Lancet · 2004 · 1.1K citations

Life Sciences, Genetics, Neuroscience +16

Dopamine-dependent neurotoxicity of α-synuclein: A mechanism for selective neurodegeneration in Parkinson disease

Jin Xu, Shyan‐Yuan Kao, Frank J.S. Lee et al. · Nature Medicine · 2002 · 768 citations

Life Sciences, Neurobiology, Neuroscience +16