Causal relation between α-synuclein locus duplication as a cause of familial Parkinson's disease

Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease

Mihael H. Polymeropoulos, Christian Lavedan, Elisabeth Leroy et al. · Science · 1997 · 8.2K citations

Life Sciences, Genetics, Molecular Genetics +17

α-Synuclein Locus Triplication Causes Parkinson's Disease

Andrew Singleton, Matthew J. Farrer, Janel Johnson et al. · Science · 2003 · 4.4K citations

Life Sciences, Genetics, Neuroscience +15

Comparison of kindreds with parkinsonism and α‐synuclein genomic multiplications

Matthew J. Farrer, Jennifer M. Kachergus, Lysia S. Forno et al. · Annals of Neurology · 2004 · 696 citations

Life Sciences, Genetics, Molecular Genetics +17

Sequencing of the alpha-synuclein gene in a large series of cases of familial Parkinson's disease fails to reveal any further mutations. The European Consortium on Genetic Susceptibility in Parkinson's Disease (GSPD)

Jenny Vaughan · Human Molecular Genetics · 1998 · 116 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15