15-Hydroxyeicosatetraenoic Acid Is a Preferential Peroxisome Proliferator-Activated Receptor β/δ Agonist

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

Ji-Hu Zhang, Thomas D.Y. Chung, Kevin R. Oldenburg · SLAS DISCOVERY · 1999 · 6.9K citations · Full text

Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ

Barry M. Forman, Jasmine Chen, Ronald M. Evans · Proceedings of the National Academy of Sciences · 1997 · 2.1K citations

Metabolic Syndrome, Health Sciences, Biochemistry +14

Oxidized LDL Regulates Macrophage Gene Expression through Ligand Activation of PPARγ

László Nagy, Peter Tontonoz, Jacqueline G. Alvarez et al. · Cell · 1998 · 1.9K citations · Full text

Inflammation, Ligand Activation, Signal Transduction +10

Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

Kazuhiko Umesono, Kevin K. Murakami, Catherine C. Thompson et al. · Cell · 1991 · 1.7K citations · Full text

Chromatin, Genetics, Retinoic Acid +5

Molecular Recognition of Fatty Acids by Peroxisome Proliferator–Activated Receptors

H. Eric Xu, Millard H. Lambert, Valerie G. Montana et al. · Molecular Cell · 1999 · 1.2K citations · Full text

Metabolic Syndrome, Lipid Synthesis, Biochemistry +1