Concepedia

Oxidized LDL Regulates Macrophage Gene Expression through Ligand Activation of PPARγ

László Nagy, Peter Tontonoz, Jacqueline G. Alvarez, Hong-Wu Chen, Ronald M. Evans

Cell · 1998 · 1.9K citations · 45 references

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45

An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-activated Receptor γ (PPARγ)

Jürgen M. Lehmann, Linda B. Moore, Tracey Smith-Oliver et al. · Journal of Biological Chemistry · 1995 · 3.6K citations · Full text

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Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor

Peter Tontonoz, Erding Hu, Bruce M. Spiegelman · Cell · 1994 · 3.5K citations

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The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation

Mercedes Ricote, Andrew C. Li, Timothy M. Willson et al. · Nature · 1998 · 3.5K citations

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PPAR-γ agonists inhibit production of monocyte inflammatory cytokines

Chengyu Jiang, Adrian T. Ting, Brian Seed · Nature · 1998 · 2.9K citations

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Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition

Joseph L. Goldstein, Y K Ho, Sandip K. Basu et al. · Proceedings of the National Academy of Sciences · 1979 · 2.5K citations · Full text

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