Discovery and characterization of potent and selective 4-oxo-4-(5-(5-phenyl-1,2,4-oxadiazol-3-yl)indolin-1-yl)butanoic acids as S1P1 agonists

Sphingosine 1-Phosphate (S1P) Receptor Subtypes S1P1 and S1P3, Respectively, Regulate Lymphocyte Recirculation and Heart Rate

Marta Sanna, Jiayu Liao, Euijung Jo et al. · Journal of Biological Chemistry · 2004 · 619 citations · Full text

FTY720 Ameliorates Th1-Mediated Colitis in Mice by Directly Affecting the Functional Activity of CD4+CD25+ Regulatory T Cells

Carolin Daniel, N Sartory, Nadine Zahn et al. · The Journal of Immunology · 2007 · 159 citations · Full text

Effect of FTY720, a novel immunosuppressant, on adjuvant-induced arthritis in rats

Mamoru Matsuura, Tomonori Imayoshi, Kenji Chiba et al. · Inflammation Research · 2000 · 69 citations

Inflammation, Rheumatology, Novel Immunosuppressant +12

FTY720 Prevents Development of Experimental Autoimmune Myocarditis Through Reduction of Circulating Lymphocytes

Hiroshi Kitabayashi, Mitsuaki Isobe, Noboru Watanabe et al. · Journal of Cardiovascular Pharmacology · 2000 · 67 citations

Cardiac Muscle, Myocarditis-affected Areas, Tacrolimus Treatment Group +18

Molecular recognition in the sphingosine 1-phosphate receptor family

Truc-Chi Pham, James I. Fells, Daniel A. Osborne et al. · Journal of Molecular Graphics and Modelling · 2007 · 36 citations · Full text

Signal Transduction, Biochemistry, G Protein-coupled Receptor +7