Effect of FTY720, a novel immunosuppressant, on adjuvant-induced arthritis in rats

The immunosuppressant FK506 selectively inhibits expression of early T cell activation genes.

Michael J. Tocci, D A Matkovich, Kathy Collier et al. · The Journal of Immunology · 1989 · 670 citations

Life Sciences, Immunology, Pharmacology +16

FTY720, a Novel Immunosuppressant, Induces Sequestration of Circulating Mature Lymphocytes by Acceleration of Lymphocyte Homing in Rats. I. FTY720 Selectively Decreases the Number of Circulating Mature Lymphocytes by Acceleration of Lymphocyte Homing

Kenji Chiba, Yoshiki Yanagawa, Yumi Masubuchi et al. · The Journal of Immunology · 1998 · 596 citations

Life Sciences, Immunology, Pharmacology +15

Risk Factors for Cyclosporine-Induced Nephropathy in Patients with Autoimmune Diseases

G Feutren, Michael J. Mihatsch · New England Journal of Medicine · 1992 · 409 citations · Full text

Medicine, Nephrology, Pharmacology +14

A Distinct Endothelial Cell Recognition System That Controls Lymphocyte Traffic into Inflamed Synovium

Sirpa Jalkanen, Allen C. Steere, R I Fox et al. · Science · 1986 · 312 citations

Medicine, Immunology, Pathology +17

Design, synthesis, and structure-activity relationships of 2-substituted-2-amino-1,3-propanediols: Discovery of a novel immunosuppressant, FTY720

Kunitomo Adachi, Toshiyuki Kohara, Noriyoshi Nakao et al. · Bioorganic & Medicinal Chemistry Letters · 1995 · 308 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14