Jeanne Moody

Discovery of APD334: Design of a Clinical Stage Functional Antagonist of the Sphingosine-1-phosphate-1 Receptor

Daniel J. Buzard, Sun Hee Kim, Luis Lopez et al. · ACS Medicinal Chemistry Letters · 2014 · 70 citations · Full text

Immunology, Potent Functional Antagonist, Inflammation +20

Fused tricyclic indoles as S1P1 agonists with robust efficacy in animal models of autoimmune disease

Daniel J. Buzard, Sangdon Han, Luis Lopez et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 18 citations · Full text

Clinical Immunology, Inflammation, Molecular Immunology +9

Design and synthesis of new tricyclic indoles as potent modulators of the S1P1 receptor

Daniel J. Buzard, Thomas O. Schrader, Xiuwen Zhu et al. · Bioorganic & Medicinal Chemistry Letters · 2014 · 18 citations · Full text

New Tricyclic Indoles, Biochemistry, Functional Selectivity +5

(7-Benzyloxy-2,3-dihydro-<i>1H</i>-pyrrolo[1,2-<i>a</i>]indol-1-yl)acetic Acids as S1P₁ Functional Antagonists

Daniel J. Buzard, Luis Lopez, Jeanne Moody et al. · ACS Medicinal Chemistry Letters · 2014 · 16 citations · Full text

S1p1 Functional Antagonists, Molecular Pharmacology, Medicinal Chemistry +15

Discovery and characterization of potent and selective 4-oxo-4-(5-(5-phenyl-1,2,4-oxadiazol-3-yl)indolin-1-yl)butanoic acids as S1P1 agonists

Daniel J. Buzard, Sangdon Han, Lars Thoresen et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 10 citations · Full text

S1p1 Agonists, Medicinal Chemistry, Butanoic Acids +8