Concepedia

Sensitivity of malignant rhabdoid tumor cell lines to PD 0332991 is inversely correlated with p16 expression

Yoshiki Katsumi, Tomoko Iehara, Mitsuru Miyachi, Shigeki Yagyu, Satoko Tsubai-Shimizu, Ken Kikuchi, Shinichi Tamura, Yasumichi Kuwahara, Kunihiko Tsuchiya, Hiroshi Kuroda,

Biochemical and Biophysical Research Communications · 2011 · 45 citations · 24 references

DOI

Concepts

References

24

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

Jacqueline J.L. Jacobs, Karin Kieboom, Silvia Marino et al. · Nature · 1999 · 1.6K citations

, , +13

Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer

Isabella Versteege, Nicolas Sévenet, Julian Lange et al. · Nature · 1998 · 1.5K citations

, , +12

PD 0332991, a selective cyclin D kinase 4/6 inhibitor, preferentially inhibits proliferation of luminal estrogen receptor-positive human breast cancer cell lines in vitro

Richard S. Finn, Judy Dering, Dylan Conklin et al. · Breast Cancer Research · 2009 · 1.4K citations · Full text

, , +17

Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts

David W. Fry, Patricia J. Harvey, Paul R. Keller et al. · Molecular Cancer Therapeutics · 2004 · 1.2K citations

, , +16

Therapeutic CDK4/6 inhibition in breast cancer: key mechanisms of response and failure

Jeffry L. Dean, Chellappagounder Thangavel, A. Kathleen McClendon et al. · Oncogene · 2010 · 403 citations

, , +16