Concepedia

A Susceptibility Gene Set for Early Onset Colorectal Cancer That Integrates Diverse Signaling Pathways: Implication for Tumorigenesis

Hong Yi, Kok Sun Ho, Kong Weng Eu, Peh Yean Cheah

Clinical Cancer Research · 2007 · 206 citations · 24 references

DOI

Abstract

The data suggest that the patient's mucosa is primed for tumorigenesis when cellular homeostasis is disrupted, and that the seven overexpressed genes could potentially predict early onset CRC.

References

24

Environmental and Heritable Factors in the Causation of Cancer — Analyses of Cohorts of Twins from Sweden, Denmark, and Finland

Paul Lichtenstein, Niels V. Holm, Pia K. Verkasalo et al. · New England Journal of Medicine · 2000 · 4.1K citations

Transcriptional gene expression profiles of colorectal adenoma, adenocarcinoma, and normal tissue examined by oligonucleotide arrays.

Daniel A. Notterman, Uri Alon, A J Sierk et al. · PubMed · 2001 · 604 citations

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Gene Expression Profiles and Molecular Markers To Predict Recurrence of Dukes' B Colon Cancer

Yixin Wang, Tim Jatkoe, Yi Zhang et al. · Journal of Clinical Oncology · 2004 · 459 citations

Allelic Variation in Gene Expression Is Common in the Human Genome

H. Shuen Lo, Zhining Wang, Ying Hu et al. · Genome Research · 2003 · 449 citations · Full text

, , +16

Transcription factor Egr-1 supports FGF-dependent angiogenesis during neovascularization and tumor growth

Roger G. Fahmy, Crispin R. Dass, Lunquan Sun et al. · Nature Medicine · 2003 · 366 citations

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