Dynamics of the p53-Mdm2 feedback loop in individual cells

Galit Lahav, Nitzan Rosenfeld, Alex Sigal, +4

Nature Genetics

P53-mdm2 Feedback LoopCell CycleTumor SuppressorMedicineCell Biology +2

Oscillations and variability in the p53 system

Naama Geva‐Zatorsky, Nitzan Rosenfeld, Shalev Itzkovitz, +8

Molecular Systems Biology

Chaos TheoryP53 SystemStochastic ResonanceSystems BiologyNonlinear Oscillation

Transcriptional gene expression profiles of colorectal adenoma, adenocarcinoma, and normal tissue examined by oligonucleotide arrays.

Daniel A. Notterman, Uri Alon, A J Sierk, +1

PubMed

Colorectal AdenomaDna MicroarraysPathologyGene Expression ProfilingTumor Biology +14

Generation of oscillations by the p53-Mdm2 feedback loop: A theoretical and experimental study

Ruth Lev Bar‐Or, Ruth Maya, Lee A. Segel, +3

Proceedings of the National Academy of Sciences

A module of negative feedback regulators defines growth factor signaling

Ido Amit, Ami Citri, Tal Shay, +15

Nature Genetics

Negative Feedback RegulatorsSystems BiologySignal TransductionSignaling PathwayCellular Regulatory Mechanism +6

Cancer-associated fibroblast compositions change with breast cancer progression linking the ratio of S100A4+ and PDPN+ CAFs to clinical outcome

Gil Friedman, Oshrat Levi-Galibov, Eyal David, +18

Nature Cancer

Breast OncologyMedicineCancer-associated Fibroblast CompositionsCancer GrowthPathology +8

The tumor microenvironment shows a hierarchy of cell-cell interactions dominated by fibroblasts

Shimrit Mayer, Tomer Milo, Achinoam Isaacson, +9

Nature Communications

Senescent cell turnover slows with age providing an explanation for the Gompertz law

Omer Karin, Amit Agrawal, Ziv Porat, +2

Nature Communications

Scale invariant mixing rates of hydrodynamically unstable interfaces

Uri Alon, J. Hecht, David Mukamel, +1

Physical Review Letters

Rarefied FlowAeroacousticsBubble DynamicEngineeringPhysics +13

Hormone seasonality in medical records suggests circannual endocrine circuits

Avichai Tendler, A. Bar, Netta Mendelsohn‐Cohen, +8

Proceedings of the National Academy of Sciences