Endotoxin Tolerance Induced by Lipopolysaccharides Derived from Porphyromonas gingivalis and Escherichia coli: Alternations in Toll-Like Receptor 2 and 4 Signaling Pathway

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

Ruslan Medzhitov, Paula Preston‐Hurlburt, Charles A. Janeway · Nature · 1997 · 5.5K citations

Life Sciences, Immunology, Molecular Biology +13

Toll-like receptor 2–mediated NF-κB activation requires a Rac1-dependent pathway

Laurence Arbibe, Jean‐Paul Mira, Nicole Teusch et al. · Nature Immunology · 2000 · 664 citations

Life Sciences, Immunology, Molecular Biology +14

Periodontal Diseases in the United States Population

Richard Oliver, Linda J. Brown, Harald Löe · Journal of Periodontology · 1998 · 427 citations

Dentistry, Periodontics, Oral Epidemiology +4

Cooperation of Toll-Like Receptor 2 and 6 for Cellular Activation by Soluble Tuberculosis Factor and <i>Borrelia burgdorferi</i> Outer Surface Protein A Lipoprotein: Role of Toll-Interacting Protein and IL-1 Receptor Signaling Molecules in Toll-Like Receptor 2 Signaling

Yonca Bulut, Emmanuelle Faure, Lisa Thomas et al. · The Journal of Immunology · 2001 · 385 citations · Full text

Life Sciences, Immunology, Infectious Diseases +17

Adaptation to bacterial lipopolysaccharide controls lipopolysaccharide-induced tumor necrosis factor production in rabbit macrophages.

John C. Mathison, G. Duke Virca, Eliza B. Wolfson et al. · Journal of Clinical Investigation · 1990 · 206 citations · Full text

Life Sciences, Immunology, Pharmacology +12