OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells

Repeat instability: mechanisms of dynamic mutations

Christopher E. Pearson, Kerrie Nichol Edamura, John D. Cleary · Nature Reviews Genetics · 2005 · 914 citations

Life Sciences, Genetics, Molecular Biology +12

Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage

Arne Klungland, Ian Rosewell, Stephan Hollenbach et al. · Proceedings of the National Academy of Sciences · 1999 · 798 citations

Life Sciences, Genetics, Molecular Biology +17

Repeat instability : mechanisms of dynamic mutations

Christopher E. Pearson · Medical Entomology and Zoology · 2005 · 711 citations

Life Sciences, Genetics, Molecular Biology +12

Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA

Tapas K. Hazra, Tadahide Izumi, István Boldogh et al. · Proceedings of the National Academy of Sciences · 2002 · 496 citations · Full text

Life Sciences, Genetics, Molecular Biology +15

Msh2 deficiency prevents in vivo somatic instability of the CAG repeat in Huntington disease transgenic mice

Kevin Manley, Thomas L. Shirley, Lorraine Flaherty et al. · Nature Genetics · 1999 · 418 citations

Life Sciences, Genetics, Molecular Genetics +12