The protective Th1 response in mice is induced in the T-cell zone only three weeks after infection with Leishmania major and not during early T-cell activation

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

Timothy R. Mosmann, Holly Cherwinski, M W Bond et al. · The Journal of Immunology · 1986 · 7.5K citations

Life Sciences, Cell Biology, Immunology +16

Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets.

Frederick P. Heinzel, M D Sadick, B J Holaday et al. · The Journal of Experimental Medicine · 1989 · 1.5K citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +17

Monocyte-Derived Dendritic Cells Formed at the Infection Site Control the Induction of Protective T Helper 1 Responses against Leishmania

Beatriz León, María López‐Bravo, Carlos Ardavı́n · Immunity · 2007 · 692 citations · Full text

Life Sciences, Immunology, Infectious Diseases +16

Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism.

M D Sadick, Frederick P. Heinzel, B J Holaday et al. · The Journal of Experimental Medicine · 1990 · 623 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +17

IFN-gamma modulates the early development of Th1 and Th2 responses in a murine model of cutaneous leishmaniasis

Phillip Scott · The Journal of Immunology · 1991 · 528 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +17