Release of matrix metalloproteinases following alcohol septal ablation in hypertrophic obstructive cardiomyopathy

Targeted deletion of matrix metalloproteinase-9 attenuates left ventricular enlargement and collagen accumulation after experimental myocardial infarction

Anique Ducharme, Stefan Frantz, Masanori Aikawa et al. · Journal of Clinical Investigation · 2000 · 808 citations · Full text

Medicine, Cardiology, Pathobiology +12

Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure

Stéphane Heymans, Aernout Luttun, Dieter Nuyens et al. · Nature Medicine · 1999 · 797 citations

Medicine, Cardiology, Pharmacology +14

Oxidative stress regulates collagen synthesis and matrix metalloproteinase activity in cardiac fibroblasts

Deborah A. Siwik, Patrick J. Pagano, Wilson S. Colucci · American Journal of Physiology-Cell Physiology · 2001 · 668 citations

Life Sciences, Biochemistry, Cardiology +17

Peripheral blood levels of matrix metalloproteases-2 and -9 are elevated in patients with acute coronary syndromes

Hisashi Kai, Hisao Ikeda, Hideo Yasukawa et al. · Journal of the American College of Cardiology · 1998 · 592 citations

Medicine, Cardiology, Internal Medicine +10

Human 72-kilodalton type IV collagenase forms a complex with a tissue inhibitor of metalloproteases designated TIMP-2.

Gregory I. Goldberg, Barry L. Marmer, Gregory A. Grant et al. · Proceedings of the National Academy of Sciences · 1989 · 586 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +8