Francis G. Spinale

Pathophysiologically Relevant Concentrations of Tumor Necrosis Factor-α Promote Progressive Left Ventricular Dysfunction and Remodeling in Rats

Biykem Bozkurt, Scott B. Kribbs, Fred J. Clubb et al. · Circulation · 1998 · 817 citations · Full text

Life Sciences, Cardiology, Physiology +13

A Matrix Metalloproteinase Induction/Activation System Exists in the Human Left Ventricular Myocardium and Is Upregulated in Heart Failure

Francis G. Spinale, Mytsi L. Coker, Lena J. Heung et al. · Circulation · 2000 · 477 citations

Medicine, Cardiology, Cardio-oncology +6

Injectable and bioresponsive hydrogels for on-demand matrix metalloproteinase inhibition

Brendan P. Purcell, David C. Lobb, Manoj B. Charati et al. · Nature Materials · 2014 · 476 citations · Full text

Engineering, Bioengineering, Biomedical Engineering +14

Increased Matrix Metalloproteinase Activity and Selective Upregulation in LV Myocardium From Patients With End-Stage Dilated Cardiomyopathy

Chadwick V. Thomas, Mytsi L. Coker, James L. Zellner et al. · Circulation · 1998 · 444 citations

Medicine, Cardiology, Internal Medicine +10

Primary Results From the SmartDelay Determined AV Optimization: A Comparison to Other AV Delay Methods Used in Cardiac Resynchronization Therapy (SMART-AV) Trial

Kenneth A. Ellenbogen, Michael R. Gold, Timothy E. Meyer et al. · Circulation · 2010 · 409 citations · Full text

Medicine, Cardiology, Clinical Cardiology +12