Concepedia

Osmolyte effects on protein stability and solubility: A balancing act between backbone and side-chains

Matthew Auton, Jörg Rösgen, Mikhail Sinev, Luis Marcelo F. Holthauzen, D. Wayne Bolen

Biophysical Chemistry · 2011 · 260 citations · 51 references

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51

Living with Water Stress: Evolution of Osmolyte Systems

Paul H. Yancey, Mary E. Clark, Steven C. Hand et al. · Science · 1982 · 3.8K citations

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Unfolding free energy changes determined by the linear extrapolation method. 1. Unfolding of phenylmethanesulfonyl .alpha.-chymotrypsin using different denaturants

Marcelo M. Santoro, D. Wayne Bolen · Biochemistry · 1988 · 1.6K citations

, , +7

PROTEINS, AMINO ACIDS AND PEPTIDES as Ions and Dipolar Ions

Edwin J. Cohn, John T. Edsall, John G. Kirkwood et al. · The American Journal of the Medical Sciences · 1943 · 911 citations

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Urea and Guanidine Hydrochloride Denaturation of Ribonuclease, Lysozyme, α-Chymotrypsin, and b-Lactoglobulin

Raymond F. Greene, C. Nick Pace · Journal of Biological Chemistry · 1974 · 805 citations · Full text

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Biochemical adaptation: Mechanism and process in physiological evolution

José Viña · Biochemistry and Molecular Biology Education · 2002 · 753 citations · Full text

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