Concepedia

Paraoxonase 1 (PON1) enhances HDL-mediated macrophage cholesterol efflux via the ABCA1 transporter in association with increased HDL binding to the cells: a possible role for lysophosphatidylcholine

Mira Rosenblat, Jacob Vaya, Diana M. Shih

Atherosclerosis · 2004 · 205 citations · 36 references

DOI

Concepts

References

36

Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions. A possible peroxidative role for paraoxonase.

Mira Rosenblat, C L Bisgaier, Roger S. Newton et al. · Journal of Clinical Investigation · 1998 · 1.2K citations · Full text

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Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis

Diana M. Shih, Lingjie Gu, Yu-Rong Xia et al. · Nature · 1998 · 1.1K citations

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Purification of human serum paraoxonase/arylesterase. Evidence for one esterase catalyzing both activities.

K Gan, Andrew Smolen, H W Eckerson et al. · Drug Metabolism and Disposition · 1991 · 595 citations

, , +16

Specific Binding of ApoA-I, Enhanced Cholesterol Efflux, and Altered Plasma Membrane Morphology in Cells Expressing ABC1

Nan Wang, David L. Silver, Philippe Costet et al. · Journal of Biological Chemistry · 2000 · 572 citations · Full text

, , +17

ABCA1 Is the cAMP-inducible Apolipoprotein Receptor That Mediates Cholesterol Secretion from Macrophages

John F. Oram, Richard M. Lawn, Michael R. Garvin et al. · Journal of Biological Chemistry · 2000 · 533 citations · Full text

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