John F. Oram

Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL

Tomáš Vaisar, Subramaniam Pennathur, Pattie S. Green et al. · Journal of Clinical Investigation · 2007 · 932 citations · Full text

Healthy Subjects, Protease Inhibition, Immunology +20

The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway

Richard M. Lawn, David P. Wade, Michael R. Garvin et al. · Journal of Clinical Investigation · 1999 · 725 citations · Full text

Molecular Physiology, Disease Mechanism, Lipid Synthesis +14

ABCA1 Is the cAMP-inducible Apolipoprotein Receptor That Mediates Cholesterol Secretion from Macrophages

John F. Oram, Richard M. Lawn, Michael R. Garvin et al. · Journal of Biological Chemistry · 2000 · 533 citations · Full text

Immunology, Lipid Movement, Cholesterol Secretion +19

The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport

Constanze Bergt, Subramaniam Pennathur, Xiaoyun Fu et al. · Proceedings of the National Academy of Sciences · 2004 · 449 citations · Full text

Human Artery Wall, Lipid Peroxidation, Immunology +17

Defective removal of cellular cholesterol and phospholipids by apolipoprotein A-I in Tangier Disease.

Gordon A. Francis, Robert H. Knopp, John F. Oram · Journal of Clinical Investigation · 1995 · 420 citations · Full text

Lipid Disorder, Oxysterol, Allergy +14