Arsenic Trioxide Induces G2/M Growth Arrest and Apoptosis after Caspase-3 Activation and Bcl-2 Phosphorylation in Promonocytic U937 Cells

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The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor α gene to a novel transcribed locus

Hugues de Thé, Christine Chomienne, Michel Lanotte et al. · Nature · 1990 · 1.4K citations

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Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization

Ella Bossy‐Wetzel · The EMBO Journal · 1998 · 1.2K citations · Full text

Signal Transduction, Mitochondrial Function, Biochemistry +11

Complete Remission after Treatment of Acute Promyelocytic Leukemia with Arsenic Trioxide

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