Yun‐Jung Choi

Molecular mechanisms of curcumin-induced cytotoxicity: induction of apoptosis through generation of reactive oxygen species, down-regulation of Bcl-XL and IAP, the release of cytochrome c and inhibition of Akt

Ju-Hyung Woo, Young Ho Kim, Yun‐Jung Choi et al. · Carcinogenesis · 2003 · 443 citations · Full text

Life Sciences, Oncology, Pharmacology +17

A Phase 3 Trial of Seladelpar in Primary Biliary Cholangitis

Gideon M. Hirschfield, Christopher L. Bowlus, Marlyn J. Mayo et al. · New England Journal of Medicine · 2024 · 235 citations

Medicine, Pharmacology, Pharmacotherapy +10

Human adipose mesenchymal stem cell-derived exosomal-miRNAs are critical factors for inducing anti-proliferation signalling to A2780 and SKOV-3 ovarian cancer cells

Abu Musa Md Talimur Reza, Yun‐Jung Choi, Hideyo Yasuda et al. · Scientific Reports · 2016 · 233 citations · Full text

Life Sciences, Biomedical Sciences, Cell Biology +17

Seladelpar (MBX-8025), a selective PPAR-δ agonist, in patients with primary biliary cholangitis with an inadequate response to ursodeoxycholic acid: a double-blind, randomised, placebo-controlled, phase 2, proof-of-concept study

David Jones, Pol Boudes, Mark G. Swain et al. · ˜The œLancet. Gastroenterology & hepatology · 2017 · 186 citations

Medicine, Pharmacology, Pharmacotherapy +12

MBX-8025, A Novel Peroxisome Proliferator Receptor-δ Agonist: Lipid and Other Metabolic Effects in Dyslipidemic Overweight Patients Treated with and without Atorvastatin

Harold Bays, Sherwyn Schwartz, Thomas Littlejohn et al. · The Journal of Clinical Endocrinology & Metabolism · 2011 · 148 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +17