Systemic administration of liposome‐encapsulated OK‐432 prolongs the survival of rats with hepatocellular carcinoma through the induction of IFN‐<b>γ</b>‐producing hepatic lymphocytes

Abstract

These findings showed that systemic administration of OK-Lipo contributed to prolonging the survival of rats with HCC. OK-Lipo induced NK cells and IFN-gamma-producing cells specifically in the liver and these cells seemed to reduce hepatocarcinogenesis and tumor growth.