CD1d-Restricted and TCR-Mediated Activation of V _α 14 NKT Cells by Glycosylceramides

Tetsu Kawano, Junqing Cui, Yasuhiko Koezuka, +9

Science

Adaptive Immune SystemImmune RegulationImmunologyNk CellsImmunologic Mechanism +15

Requirement for V _α 14 NKT Cells in IL-12-Mediated Rejection of Tumors

Junqing Cui, Tahiro Shin, Tetsu Kawano, +7

Science

Differential Tumor Surveillance by Natural Killer (Nk) and Nkt Cells

Mark J. Smyth, Kevin Thia, Shayna E.A. Street, +7

The Journal of Experimental Medicine

ImmunologyNk CellsPathologyImmunologic MechanismImmunotherapy +14

The Natural Killer T (NKT) Cell Ligand α-Galactosylceramide Demonstrates Its Immunopotentiating Effect by Inducing Interleukin (IL)-12 Production by Dendritic Cells and IL-12 Receptor Expression on NKT Cells

Hidemitsu Kitamura, Kenji Iwakabe, Takashi Yahata, +10

The Journal of Experimental Medicine

Natural killer-like nonspecific tumor cell lysis mediated by specific ligand-activated Vα14 NKT cells

Tetsu Kawano, Junqing Cui, Yasuhiko Koezuka, +9

Proceedings of the National Academy of Sciences

Cancer ImmunosurveillanceImmunologyTumor ImmunityCell DeathValpha14 Nkt Cells +11

Augmentation of Vα14 Nkt Cell–Mediated Cytotoxicity by Interleukin 4 in an Autocrine Mechanism Resulting in the Development of Concanavalin a–Induced Hepatitis

Yoshikatsu Kaneko, Michishige Harada, Tetsu Kawano, +5

The Journal of Experimental Medicine

Liver FibrosisImmunologyCell DeathPathologyAutocrine Mechanism Resulting +20

Selective reduction of V α 14+ NK T cells associated with disease development in autoimmune-prone mice

Marco Antonio Mieza, Toshiyuki Itoh, J. Cui, +9

The Journal of Immunology

Cutting edge: inhibition of experimental tumor metastasis by dendritic cells pulsed with alpha-galactosylceramide.

Isao Toura, Tetsu Kawano, Yasunori Akutsu, +3

PubMed

ImmunologyImmunologic MechanismImmunotherapyTumor BiologyValpha14 Nkt Cells +16

Antitumor cytotoxicity mediated by ligand-activated human V alpha24 NKT cells.

Tetsu Kawano, Toshinori Nakayama, Noriaki Kamada, +10

PubMed

Cancer ResearchRadiation OncologyCell TherapyCancer ImmunosurveillanceImmunology +13

Cutting Edge: Inhibition of Experimental Tumor Metastasis by Dendritic Cells Pulsed with α-Galactosylceramide

Isao Toura, Tetsu Kawano, Yasunori Akutsu, +3

The Journal of Immunology

ImmunologyImmune RegulationImmunotherapeuticsImmunotherapyTumor Biology +18